Dementia in LMICs may be a syndemic: a "Population Neuroscience–Dementia Syndemics" framework links women’s risk to interacting diseases, stress pathways, and structural factors like poverty and environment

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Nature, Published online: 27 February 2026; doi:10.1038/d41586-026-00621-w

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For implementers, the locking model adds a fair amount of non-trivial internal bookkeeping. Every operation must check lock state, readers must be tracked, and the interplay between locks, cancellation, and error states creates a matrix of edge cases that must all be handled correctly.