This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.
around a year ago, we built a regex engine in F# that not only outperformed the ones in dotnet, but went above and beyond competing with every other industrial regex engine on a large set of industry-standard benchmarks. additionally, it supports the full set of boolean operators (union, intersection, complement) and even a form of context-aware lookarounds, which no other engine has while preserving O(n) search-time complexity. the paper was published at POPL 2025, and i figured it’s time to open source the engine and share the story behind it. consider it a much more casual and chatty version of the paper, with more focus on engineering aspects that went into it.
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NYT Connections Sports Edition today: Hints and answers for February 26
2026-03-03 00:00:00:03014310710http://paper.people.com.cn/rmrb/pc/content/202603/03/content_30143107.htmlhttp://paper.people.com.cn/rmrb/pad/content/202603/03/content_30143107.html11921 我国成为发布大模型最多的国家